Systematic exploration of guide-tree topology effects for small protein alignments
نویسندگان
چکیده
منابع مشابه
The effect of the guide tree on multiple sequence alignments and subsequent phylogenetic analyses.
Many multiple sequence alignment methods (MSAs) use guide trees in conjunction with a progressive alignment technique to generate a multiple sequence alignment but use differing techniques to produce the guide tree and to perform the progressive alignment. In this paper we explore the consequences of changing the guide tree used for the alignment routine. We evaluate four leading MSA methods (P...
متن کاملThe Effect of the Guide Tree on Multiple Sequence Alignments and Subsequent Phylogenetic Analysis
Many multiple sequence alignment methods (MSAs) use guide trees in conjunction with a progressive alignment technique to generate a multiple sequence alignment but use differing techniques to produce the guide tree and to perform the progressive alignment. In this paper we explore the consequences of changing the guide tree used for the alignment routine. We evaluate four leading MSA methods (P...
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ژورنال
عنوان ژورنال: BMC Bioinformatics
سال: 2014
ISSN: 1471-2105
DOI: 10.1186/1471-2105-15-338